As I said, my settings were out-of-the-box.
Search and replace string did not include regex
ex. Replace AND with XXXXXXXXXX
My environment is Vista 64-bit, but I do not think that has anything to do with it since the other programs are 32-bit as well so some thunking should be taking place.
I have 1 million line text (81MB), and did a simple replace (Replace “abc” with “XXXXXXXXXX”). In my machine it took about 8 seconds (when “Match Case” is off), and 3 seconds (when “Match Case” is on). Is this comparable to your results? You might want to try “Match Case” on, since this changes the speed dramatically. I will still look into more details. Thank you!